Microneedling & Advanced Regenerative Therapies PRP · Hyaluronic Acid · PDRN · Exosomes · Custom Serums

Collagen induction with platelet-rich plasma

Stimulate collagen. Support recovery. Reveal radiant, rejuvenated skin.

About This Treatment

Microneedling is a powerful, minimally invasive treatment that creates controlled micro-injuries in the skin, triggering your body’s natural healing response and stimulating collagen and elastin production. When combined with advanced regenerative therapies—PRP, hyaluronic acid, PDRN (salmon DNA), custom serums, or exosomes—the results are amplified, delivering deeper rejuvenation, faster recovery, and more radiant skin.

At Skinovatio Ohio, we customize every microneedling treatment to your unique skin concerns and goals. Whether you’re seeking to reduce fine lines, improve texture, fade scars, or simply achieve a healthy, luminous glow, we have a protocol designed for you.

Microneedling with PRP (Platelet-Rich Plasma)

PRP enhances microneedling by using your body’s own growth factors to accelerate healing and amplify collagen production.

Benefits of Microneedling with PRP:

 
 
BenefitWhat It Means for You
Collagen BoostStimulates natural collagen production for firmness and elasticity
Improved TextureRefines skin texture for a smoother, softer complexion
Reduced Fine Lines & WrinklesMinimizes visible signs of aging
Enhanced Skin ToneAddresses hyperpigmentation and discoloration
Natural HealingUses your body’s own platelets to accelerate rejuvenation
Minimal DowntimeReturn to your routine quickly

Microneedling with Hyaluronic Acid

Hyaluronic acid (HA) is a naturally occurring substance that attracts and holds moisture in the skin. When delivered via microneedling, HA penetrates deep into the dermis for intense, lasting hydration.

Benefits of Microneedling with HA:

 
 
BenefitWhat It Means for You
Deep HydrationAttracts and binds moisture for plump, supple skin
Improved ElasticityRestores bounce and resilience
Smoother TextureReduces fine lines and rough patches
Radiant GlowEnhances overall skin luminosity

Microneedling with PDRN (Salmon DNA)

PDRN (polydeoxyribonucleotides) is derived from salmon DNA and is rich in nucleotides that promote cellular regeneration and tissue repair. This advanced therapy has been shown to significantly improve skin hydration, elasticity, and overall quality, with visible results within 8 weeks.

Benefits of Microneedling with PDRN:

 
 
BenefitWhat It Means for You
Cellular RegenerationPromotes DNA repair and tissue regeneration
Reduced InflammationCalms redness and irritation
Improved Skin TextureSmooths and refines skin surface
Enhanced ElasticityRestores firmness and bounce
Accelerated HealingSupports faster recovery after treatment

Key Fact: PDRN therapy has been shown to significantly improve skin hydration, elasticity, and overall skin quality, with visible results within 8 weeks.

Microneedling with Exosomes

Exosomes are tiny extracellular vesicles that act as messengers between cells, delivering growth factors, proteins, and genetic material directly to skin cells. They have been shown to significantly reduce the appearance of fine lines, wrinkles, and pigmentation, resulting in smoother, more radiant skin.

Benefits of Microneedling with Exosomes:

 
 
BenefitWhat It Means for You
Advanced Cellular CommunicationDelivers growth factors to targeted areas
Enhanced Collagen ProductionStimulates firmer, more resilient skin
Reduced HyperpigmentationFades dark spots and uneven tone
Accelerated HealingSupports faster recovery after treatment
Overall Skin RejuvenationSmoother, more radiant skin
Improves Skin Elasticity and FirmnessRestores a youthful, vibrant appearance

Key Fact: A 2024 case series demonstrated that rose stem-cell-derived exosomes combined with microneedling resulted in significant improvements in skin texture and radiance within 12 weeks.

Microneedling with Custom Serums

We also offer microneedling with customized serums tailored to your specific skin concerns. Whether you’re targeting acne, pigmentation, or aging, we create a personalized blend of active ingredients to address your unique needs.

 
 
Custom Serum FocusKey Ingredients
Acne & CongestionSalicylic acid, niacinamide
HyperpigmentationVitamin C, tranexamic acid, kojic acid
Aging & Fine LinesPeptides, growth factors, retinol
Sensitive SkinCentella asiatica, ceramides, soothing botanicals

The Microneedling Process

Consultation

We assess your skin type, concerns, and goals to determine the ideal combination therapy for you.

Treatment

  • Duration: 45–60 minutes

  • Comfort: Topical numbing ensures a comfortable experience

  • Process: A sterile microneedling device creates controlled micro-injuries while the selected serum/PRP/exosomes is infused into the skin

Recovery

  • Immediate: Mild redness and sensitivity (similar to a mild sunburn) for 24–48 hours

  • Downtime: Minimal—most patients return to normal activities within 24–48 hours

  • Results: Progressive improvement over 3–6 weeks

Results Timeline

 
 
PhaseWhat to Expect
Days 1–3Mild redness, tightness
Week 1Initial glow, improved texture
Weeks 3–6Collagen builds, results become visible
Months 3–6Optimal results with multiple sessions

Who Is a Good Candidate?

Microneedling with regenerative therapies is suitable for most skin types and can address a wide range of concerns:

 
 
ConcernRecommended Therapy
Aging SkinPRP, Exosomes, Custom Serums
Fine Lines & WrinklesPRP, Exosomes, HA
Acne ScarsPRP, Exosomes, PDRN
HyperpigmentationCustom Serums, Exosomes
Dull, Dehydrated SkinHA, Custom Serums
Uneven TexturePRP, PDRN, Exosomes

Recommended Treatment Series

  • Initial Series: 3–4 treatments, spaced 4–6 weeks apart

  • Maintenance: 1–2 treatments annually

Why Choose Skinovatio Ohio?

 
 
ReasonWhat It Means for You
Medical ExpertiseTreatments performed by trained professionals under physician supervision
Advanced Regenerative TherapiesWe offer PRP, PDRN, exosomes, and custom serums
Personalized ApproachEvery treatment is tailored to your unique skin concerns
Premium ProductsWe use medical-grade serums and growth factors
Safety FirstSterile, single-use needles for every patient
Proven ResultsReal improvements in skin texture, tone, and radiance

Frequently Asked Questions

What is PRP?
PRP (platelet-rich plasma) is a concentration of your own platelets and growth factors, derived from a small sample of your blood. It accelerates healing and stimulates collagen production.

What is PDRN?
PDRN (polydeoxyribonucleotides) is a DNA-derived compound that promotes cellular regeneration and tissue repair, with significant benefits for skin hydration, elasticity, and overall skin quality.

What are exosomes?
Exosomes are tiny vesicles that carry growth factors, proteins, and genetic material between cells. They enhance collagen production, improve skin texture, and reduce pigmentation.

Does it hurt?
Topical numbing is applied before treatment. Most patients describe the sensation as a mild vibration or light pressure.

How many treatments do I need?
A series of 3–4 treatments, spaced 4–6 weeks apart, is recommended for optimal results.

Is there downtime?
Minimal downtime. Mild redness and sensitivity may occur for 24–48 hours after treatment.

Can I combine microneedling with other treatments?
Yes. Microneedling complements other aesthetic treatments like chemical peels, laser, or injectables.


Book Your Consultation

Ready to rejuvenate your skin with advanced microneedling therapies?

📍 Skinovatio Ohio
1139 Rockside Rd., Parma, OH 44134
📞 216-712-4605
📧 info@skinovatioohio.com

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Service(s) of Interest

RESULTS

Before & After

See real results from our patients. Individual results may vary.

Before Microneedling with PRP treatment — example #1
Before
After Microneedling with PRP treatment — example #1
After
Before Microneedling with PRP treatment — example #2
Before
After Microneedling with PRP treatment — example #2
After

*Results may vary. Photos are unretouched.

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Book a complimentary consultation to discuss your goals and create a personalized treatment plan.

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